| Boston Red Sox (8-10) at Chicago White Sox (10-9) |
| Game One |
Boston 10, Chicago 3 |
| Game Two |
Friday, April 27th, 8:10 p.m. |
| Game Three |
Saturday, April 28th, 7:10 p.m. |
| Game Four |
Sunday, April 29th, 2:10 p.m. |
| Records |
| 2012 Head-to-Head Record |
Boston 1-0 (0-0 at Bos; 1-0 at Chi) |
| 2011 Head-to-Head Record |
Chicago 4-2 (3-0 at Bos; 1-2 at Chi) |
| 2010 Head-to-Head Record |
Chicago 6-1 (3-0 at Bos; 3-1 at Chi) |
| 2009 Head-to-Head Record |
Tied 4-4 (Chi 1-3 at Bos; 3-1 at Home) |
| Home Record |
Boston 3-5; Chicago 3-5 |
| Away Record |
Boston 5-5; Chicago 7-4 |
| Current Streak |
Boston (W4); Chicago (L3) |
| Record vs. Central Division |
Boston 4-3 |
| Record vs. Eastern Division |
Chicago 1-4 |
| 2012 Meetings |
| 4/26 - Boston, 10-3 (at Chi - WP: Doubront; LP: Humber) |
| 2011 Meetings |
| 5/30 - Chicago, 7-3 (at Bos - WP: Peavy; LP: Lester) |
| 5/31 - Chicago, 10-7 (at Bos - WP: Humber; LP: Aceves) |
| 6/01 - Chicago, 7-4 (at Bos - WP: Floyd; LP: Albers) |
| 7/29 - Chicago, 3-1 (at Chi - WP: Floyd; LP: Wakefield) |
| 7/30 - Boston, 10-2 (at Chi - WP: Lester; LP: Humber) |
| 7/31 - Boston, 5-3 (at Chi - WP: Aceves; LP: Crain) |
| 2010 Meetings |
| 9/03 - Postponed at Boston (Made-up September 4th) |
| 9/04 - Chicago, 3-1 (at Bos - WP: Danks; LP: C.Buchholz) |
| 9/04 - Chicago, 3-1 (at Bos - WP: Floyd; LP: Lackey) |
| 9/05 - Chicago, 7-5 (at Bos - WP: Linebrink; LP: Papelbon) |
| 9/27 - Boston, 6-1 (at Chi - WP: C.Buchholz; LP: Buehrle) |
| 9/28 - Chicago, 5-4 (at Chi - WP: Sale; LP: Bowden) |
| 9/29 - Chicago, 5-2 (at Chi - WP: F.Garcia; LP: Beckett) |
| 9/30 - Chicago, 8-2 (at Chi - WP: Danks; LP: Lester) |
| 2009 Meetings |
| 8/24 - Boston, 12-8 (at Bos - WP: R.S.Ramirez; LP: Contreras) |
| 8/25 - Boston, 6-3 (at Bos - WP: Delcarmen; LP: Linebrink) |
| 8/26 - Boston, 3-2 (at Bos - WP: Bard; LP: T.Pena) |
| 8/27 - Chicago, 9-5 (at Bos - WP: Danks; LP: Tazawa) |
| 9/04 - Chicago, 12-2 (at Chi - WP: F.Garcia; LP: Byrd) |
| 9/05 - Chicago, 5-1 (at Chi - WP: Floyd; LP: Wakefield) |
| 9/06 - Boston, 6-1 (at Chi - WP: Lester; LP: Danks) |
| 9/07 - Chicago, 5-1 (at Chi - WP: Buehrle; LP: Beckett) |
| Boston last five games |
Chicago last five games |
| 4/22 - Postponed vs. NY Yankees |
4/22 - W at Seattle, 7-4 |
| 4/23 - W at Minnesota, 6-5 |
4/23 - W at Oakland, 4-0 |
| 4/24 - W at Minnesota, 11-2 |
4/24 - L at Oakland, 0-2 |
| 4/25 - W at Minnesota, 7-6 |
4/25 - L at Oakland, 4-5 (14) |
| 4/26 - W at Chicago WSox, 10-3 |
4/26 - L vs. Boston, 3-10 |