| April |
| 4/044/044/044/044/05 | vs. STL (WP: K.Lohse; LP: J.Johnson) | L - 1-4 | Wrap | Box |
| 4/054/054/054/054/05 | at CIN (WP: J.Cueto; LP: M.Buehrle) | L - 0-4 | Wrap | Box |
| 4/074/074/074/074/08 | at CIN (WP: R.Nolasco; LP: M.Latos) | W - 8-3 | Wrap | Box |
| 4/084/084/084/084/08 | at CIN (WP: A.Chapman; LP: H.Bell) | L - 5-6 | Wrap | Box |
| 4/094/094/094/094/09 | at PHI (WP: A.Sanchez; LP: C.Hamels) | W - 6-2 | Wrap | Box |
| 4/114/114/114/114/12 | at PHI (WP: R.Halladay; LP: J.Johnson) | L - 1-7 | Wrap | Box |
| 4/124/124/124/124/13 | at PHI (WP: J.Blanton; LP: M.Buehrle) | L - 1-3 | Wrap | Box |
| 4/134/134/134/134/14 | vs. HOU (WP: R.Webb; LP: B.Lyon) | W - 5-4 (11th) | Wrap | Box |
| 4/144/144/144/144/15 | vs. HOU (WP: R.Cruz; LP: H.Bell) | L - 4-5 | Wrap | Box |
| 4/154/154/154/154/15 | vs. HOU (WP: C.Gaudin; LP: D.Carpenter) | W - 5-4 (11th) | Wrap | Box |
| 4/174/174/174/174/18 | vs. CHC (WP: S.Cishek; LP: R.Dolis) | W - 5-2 | Wrap | Box |
| 4/184/184/184/184/19 | vs. CHC (WP: M.Buehrle; LP: M.Garza) | W - 9-1 | Wrap | Box |
| 4/194/194/194/194/19 | vs. CHC (WP: R.Nolasco; LP: J.Samardzija) | W - 5-3 | Wrap | Box |
| 4/204/204/204/204/21 | at WAS (WP: R.Detwiler; LP: C.Zambrano) | L - 0-2 | Wrap | Box |
| 4/214/214/214/214/21 | at WAS (WP: T.Gorzelanny; LP: E.Mujica) | L - 2-3 (10th) | Wrap | Box |
| 4/224/224/224/224/22 | at WAS | Postponed | Wrap |
| 4/244/244/244/244/25 | at NYM (WP: J.Rauch; LP: E.Mujica) | L - 1-2 | Wrap | Box |
| 4/254/254/254/254/26 | at NYM (WP: R.Dickey; LP: M.Buehrle) | L - 1-5 | Wrap | Box |
| 4/264/264/264/264/26 | at NYM (WP: R.Ramirez; LP: H.Bell) | L - 2-3 | Wrap | Box |
| 4/274/274/274/274/28 | vs. ARI (WP: J.Saunders; LP: C.Zambrano) | L - 0-5 | Wrap | Box |
| 4/284/284/284/284/29 | vs. ARI (WP: S.Cishek; LP: B.Ziegler) | W - 3-2 | Wrap | Box |
| 4/294/294/294/294/29 | vs. ARI (WP: W.Miley; LP: J.Johnson) | L - 4-8 | Wrap | Box |
| 4/304/304/304/304/30 | vs. ARI (WP: P.Corbin; LP: M.Buehrle) | L - 5-9 | Wrap | Box |
| May |
| 5/015/015/015/015/02 | at SFG (WP: R.Nolasco; LP: M.Cain) | W - 2-1 | Wrap | Box |
| 5/025/025/025/025/03 | at SFG (WP: S.Cishek; LP: S.Casilla) | W - 3-2 (10th) | Wrap | Box |
| 5/035/035/035/035/03 | at SFG (WP: A.Sanchez; LP: R.Vogelsong) | W - 3-2 | Wrap | Box |
| 5/045/045/045/045/05 | at SDP (WP: S.Cishek; LP: J.Spence) | W - 9-8 (12th) | Wrap | Box |
| 5/055/055/055/055/06 | at SDP (WP: M.Buehrle; LP: C.Richard) | W - 4-1 | Wrap | Box |
| 5/065/065/065/065/06 | at SDP (WP: R.Nolasco; LP: A.Cashner) | W - 6-3 | Wrap | Box |
| 5/075/075/075/075/08 | at HOU (WP: C.Zambrano; LP: W.Rodriguez) | W - 4-0 | Wrap | Box |
| 5/085/085/085/085/09 | at HOU (WP: W.Lopez; LP: R.Webb) | L - 2-3 | Wrap | Box |
| 5/095/095/095/095/10 | at HOU (WP: R.Webb; LP: D.Carpenter) | W - 5-3 (12th) | Wrap | Box |
| 5/115/115/115/115/12 | vs. NYM (WP: H.Bell; LP: F.Francisco) | W - 6-5 | Wrap | Box |
| 5/125/125/125/125/12 | vs. NYM (WP: R.Dickey; LP: R.Nolasco) | L - 3-9 | Wrap | Box |
| 5/135/135/135/135/13 | vs. NYM (WP: H.Bell; LP: F.Francisco) | W - 8-4 | Wrap | Box |
| 5/145/145/145/145/15 | vs. PIT (WP: B.Lincoln; LP: A.Sanchez) | L - 2-3 | Wrap | Box |
| 5/155/155/155/155/16 | vs. PIT (WP: J.Johnson; LP: K.Correia) | W - 6-2 | Wrap | Box |
| 5/165/165/165/165/17 | at ATL (WP: M.Buehrle; LP: M.Minor) | W - 8-4 | Wrap | Box |
| 5/175/175/175/175/18 | at ATL (WP: B.Beachy; LP: R.Nolasco) | L - 0-7 | Wrap | Box |
| 5/185/185/185/185/19 | at CLE (WP: C.Zambrano; LP: T.Sipp) | W - 3-2 | Wrap | Box |
| 5/195/195/195/195/19 | at CLE (WP: J.Gomez; LP: A.Sanchez) | L - 0-2 | Wrap | Box |
| 5/205/205/205/205/20 | at CLE (WP: J.Johnson; LP: D.Lowe) | W - 5-3 | Wrap | Box |
| 5/215/215/215/215/22 | vs. COL (WP: M.Buehrle; LP: J.Moyer) | W - 7-4 | Wrap | Box |
| 5/225/225/225/225/23 | vs. COL (WP: R.Nolasco; LP: J.Nicasio) | W - 7-6 | Wrap | Box |
| 5/235/235/235/235/24 | vs. COL (WP: A.White; LP: C.Zambrano) | L - 4-8 | Wrap | Box |
| 5/245/245/245/245/25 | vs. SFG (WP: R.Vogelsong; LP: A.Sanchez) | L - 7-14 | Wrap | Box |
| 5/255/255/255/255/26 | vs. SFG (WP: D.Jennings; LP: T.Lincecum) | W - 7-6 | Wrap | Box |
| 5/265/265/265/265/26 | vs. SFG (WP: M.Buehrle; LP: M.Bumgarner) | W - 5-3 | Wrap | Box |
| 5/275/275/275/275/27 | vs. SFG (WP: M.Cain; LP: R.Nolasco) | L - 2-3 | Wrap | Box |
| 5/285/285/285/285/28 | vs. WAS (WP: C.Zambrano; LP: J.Zimmermann) | W - 5-3 | Wrap | Box |
| 5/295/295/295/295/30 | vs. WAS (WP: A.Sanchez; LP: E.Jackson) | W - 3-1 | Wrap | Box |
| 5/305/305/305/305/31 | vs. WAS (WP: J.Johnson; LP: C.Wang) | W - 5-3 | Wrap | Box |
| June |
| 6/016/016/016/016/02 | at PHI (WP: K.Kendrick; LP: M.Buehrle) | L - 4-6 | Wrap | Box |
| 6/026/026/026/026/02 | at PHI (WP: R.Nolasco; LP: C.Hamels) | W - 5-4 | Wrap | Box |
| 6/036/036/036/036/03 | at PHI (WP: C.Zambrano; LP: J.Blanton) | W - 5-1 | Wrap | Box |
| 6/056/056/056/056/06 | vs. ATL (WP: T.Hudson; LP: A.Sanchez) | L - 0-11 | Wrap | Box |
| 6/066/066/066/066/07 | vs. ATL (WP: R.Delgado; LP: J.Johnson) | L - 1-2 | Wrap | Box |
| 6/076/076/076/076/08 | vs. ATL (WP: M.Minor; LP: M.Buehrle) | L - 2-8 | Wrap | Box |
| 6/086/086/086/086/09 | vs. TAM (WP: B.Badenhop; LP: R.Nolasco) | L - 1-5 | Wrap | Box |
| 6/096/096/096/096/10 | vs. TAM (WP: M.Moore; LP: C.Zambrano) | L - 4-13 | Wrap | Box |
| 6/106/106/106/106/10 | vs. TAM (WP: J.Shields; LP: A.Sanchez) | L - 2-4 | Wrap | Box |
| 6/116/116/116/116/12 | vs. BOS (WP: J.Johnson; LP: J.Beckett) | W - 4-1 | Wrap | Box |
| 6/126/126/126/126/13 | vs. BOS (WP: C.Buchholz; LP: M.Buehrle) | L - 1-2 | Wrap | Box |
| 6/136/136/136/136/14 | vs. BOS (WP: F.Doubront; LP: R.Nolasco) | L - 2-10 | Wrap | Box |
| 6/156/156/156/156/16 | at TAM (WP: M.Moore; LP: C.Zambrano) | L - 0-11 | Wrap | Box |
| 6/166/166/166/166/17 | at TAM (WP: R.Webb; LP: B.Gomes) | W - 4-3 (15th) | Wrap | Box |
| 6/176/176/176/176/17 | at TAM (WP: A.Cobb; LP: J.Johnson) | L - 0-3 | Wrap | Box |
| 6/196/196/196/196/20 | at BOS (WP: C.Buchholz; LP: M.Buehrle) | L - 5-7 | Wrap | Box |
| 6/206/206/206/206/21 | at BOS (WP: F.Doubront; LP: R.Nolasco) | L - 5-15 | Wrap | Box |
| 6/216/216/216/216/22 | at BOS (WP: S.Atchison; LP: E.Mujica) | L - 5-6 | Wrap | Box |
| 6/226/226/226/226/23 | vs. TOR (WP: R.Romero; LP: A.Sanchez) | L - 5-12 | Wrap | Box |
| 6/236/236/236/236/23 | vs. TOR (WP: D.Oliver; LP: S.Cishek) | L - 1-7 | Wrap | Box |
| 6/246/246/246/246/24 | vs. TOR (WP: M.Buehrle; LP: J.Chavez) | W - 9-0 | Wrap | Box |
| 6/256/256/256/256/26 | vs. STL (WP: V.Marte; LP: C.Gaudin) | L - 7-8 (10th) | Wrap | Box |
| 6/266/266/266/266/27 | vs. STL (WP: K.Lohse; LP: C.Zambrano) | L - 2-5 | Wrap | Box |
| 6/276/276/276/276/28 | vs. STL (WP: A.Sanchez; LP: S.Freeman) | W - 5-3 | Wrap | Box |
| 6/296/296/296/296/30 | vs. PHI (WP: J.Johnson; LP: C.Lee) | W - 6-2 | Wrap | Box |
| 6/306/306/306/306/30 | vs. PHI (WP: M.Buehrle; LP: C.Hamels) | W - 3-2 | Wrap | Box |
| July |
| 7/017/017/017/017/01 | vs. PHI (WP: R.Nolasco; LP: J.Blanton) | W - 5-2 | Wrap | Box |
| 7/027/027/027/027/03 | at MIL (WP: F.Rodriguez; LP: R.Webb) | L - 5-6 | Wrap | Box |
| 7/037/037/037/037/03 | at MIL (WP: L.Hernandez; LP: H.Bell) | L - 12-13 (10th) | Wrap | Box |
| 7/047/047/047/047/04 | at MIL (WP: W.LeBlanc; LP: M.Parra) | W - 7-6 (10th) | Wrap | Box |
| 7/057/057/057/057/05 | at MIL (WP: M.Buehrle; LP: M.Fiers) | W - 4-0 | Wrap | Box |
| 7/067/067/067/067/07 | at STL (WP: R.Nolasco; LP: J.Westbrook) | W - 3-2 | Wrap | Box |
| 7/077/077/077/077/07 | at STL (WP: K.Lohse; LP: C.Zambrano) | L - 2-3 | Wrap | Box |
| 7/087/087/087/087/08 | at STL (WP: M.Boggs; LP: H.Bell) | L - 4-5 | Wrap | Box |
| 7/137/137/137/137/14 | vs. WAS (WP: J.Zimmermann; LP: J.Johnson) | L - 1-5 | Wrap | Box |
| 7/147/147/147/147/15 | vs. WAS (WP: M.Buehrle; LP: G.Gonzalez) | W - 2-1 | Wrap | Box |
| 7/157/157/157/157/15 | vs. WAS (WP: S.Strasburg; LP: R.Nolasco) | L - 0-4 | Wrap | Box |
| 7/167/167/167/167/17 | vs. WAS (WP: C.Zambrano; LP: E.Jackson) | W - 5-3 | Wrap | Box |
| 7/177/177/177/177/18 | at CHC (WP: A.Sanchez; LP: T.Wood) | W - 9-5 | Wrap | Box |
| 7/187/187/187/187/19 | at CHC (WP: J.Russell; LP: J.Johnson) | L - 1-5 (8th) | Wrap | Box |
| 7/197/197/197/197/19 | at CHC (WP: P.Maholm; LP: M.Buehrle) | L - 2-4 | Wrap | Box |
| 7/207/207/207/207/21 | at PIT (WP: K.Correia; LP: R.Nolasco) | L - 3-4 | Wrap | Box |
| 7/217/217/217/217/22 | at PIT (WP: A.Burnett; LP: C.Zambrano) | L - 1-5 | Wrap | Box |
| 7/227/227/227/227/22 | at PIT (WP: J.Karstens; LP: A.Sanchez) | L - 0-3 | Wrap | Box |
| 7/237/237/237/237/24 | vs. ATL (WP: J.Johnson; LP: M.Minor) | W - 2-1 | Wrap | Box |
| 7/247/247/247/247/25 | vs. ATL (WP: T.Hudson; LP: W.LeBlanc) | L - 3-4 | Wrap | Box |
| 7/257/257/257/257/25 | vs. ATL (WP: T.Hanson; LP: R.Nolasco) | L - 1-7 | Wrap | Box |
| 7/277/277/277/277/28 | vs. SDP (WP: K.Wells; LP: C.Zambrano) | L - 2-7 | Wrap | Box |
| 7/287/287/287/287/29 | vs. SDP (WP: N.Eovaldi; LP: R.Ohlendorf) | W - 4-2 | Wrap | Box |
| 7/297/297/297/297/29 | vs. SDP (WP: R.Webb; LP: B.Brach) | W - 5-4 (10th) | Wrap | Box |
| 7/307/307/307/307/31 | at ATL (WP: T.Hanson; LP: M.Buehrle) | L - 2-8 | Wrap | Box |
| 7/317/317/317/318/01 | at ATL (WP: K.Medlen; LP: R.Nolasco) | L - 1-7 | Wrap | Box |
| August |
| 8/018/018/018/018/02 | at ATL (WP: C.Zambrano; LP: B.Sheets) | W - 4-2 | Wrap | Box |
| 8/028/028/028/028/03 | at ATL (WP: C.Martinez; LP: N.Eovaldi) | L - 1-6 | Wrap | Box |
| 8/038/038/038/038/03 | at WAS (WP: J.Lannan; LP: B.Hand) | L - 4-7 | Wrap | Box |
| 8/038/038/038/038/04 | at WAS (WP: J.Johnson; LP: G.Gonzalez) | W - 5-2 | Wrap | Box |
| 8/048/048/048/048/05 | at WAS (WP: R.Mattheus; LP: M.Dunn) | L - 7-10 | Wrap | Box |
| 8/058/058/058/058/05 | at WAS (WP: S.Strasburg; LP: R.Nolasco) | L - 1-4 | Wrap | Box |
| 8/078/078/078/078/08 | at NYM (WP: C.Zambrano; LP: J.Niese) | W - 4-2 | Wrap | Box |
| 8/088/088/088/088/09 | at NYM (WP: N.Eovaldi; LP: C.Young) | W - 13-0 | Wrap | Box |
| 8/098/098/098/098/09 | at NYM (WP: R.Dickey; LP: J.Johnson) | L - 1-6 | Wrap | Box |
| 8/108/108/108/108/11 | vs. LOS (WP: C.Kershaw; LP: M.Buehrle) | L - 2-5 | Wrap | Box |
| 8/118/118/118/118/12 | vs. LOS (WP: R.Nolasco; LP: J.Blanton) | W - 7-3 | Wrap | Box |
| 8/128/128/128/128/12 | vs. LOS (WP: C.Capuano; LP: W.LeBlanc) | L - 0-5 | Wrap | Box |
| 8/138/138/138/138/14 | vs. PHI (WP: C.Hamels; LP: N.Eovaldi) | L - 0-4 | Wrap | Box |
| 8/148/148/148/148/15 | vs. PHI (WP: K.Kendrick; LP: J.Johnson) | L - 0-1 | Wrap | Box |
| 8/158/158/158/158/15 | vs. PHI (WP: M.Buehrle; LP: R.Halladay) | W - 9-2 | Wrap | Box |
| 8/168/168/168/168/17 | at COL (WP: A.Ottavino; LP: R.Nolasco) | L - 3-5 | Wrap | Box |
| 8/178/178/178/178/18 | at COL (WP: W.LeBlanc; LP: J.Roenicke) | W - 6-5 | Wrap | Box |
| 8/188/188/188/188/19 | at COL (WP: N.Eovaldi; LP: T.Chatwood) | W - 6-5 | Wrap | Box |
| 8/198/198/198/198/19 | at COL (WP: A.Ottavino; LP: J.Johnson) | L - 2-3 | Wrap | Box |
| 8/208/208/208/208/21 | at ARI (WP: M.Buehrle; LP: J.Saunders) | W - 12-3 | Wrap | Box |
| 8/218/218/218/218/22 | at ARI (WP: C.Gaudin; LP: S.Demel) | W - 6-5 (10th) | Wrap | Box |
| 8/228/228/228/228/22 | at ARI (WP: T.Skaggs; LP: J.Turner) | L - 2-3 | Wrap | Box |
| 8/228/228/228/228/23 | at ARI (WP: W.Miley; LP: W.LeBlanc) | L - 0-3 | Wrap | Box |
| 8/248/248/248/248/25 | at LOS (WP: J.Wright; LP: N.Eovaldi) | L - 4-11 | Wrap | Box |
| 8/258/258/258/258/26 | at LOS (WP: C.Kershaw; LP: J.Johnson) | L - 2-8 | Wrap | Box |
| 8/268/268/268/268/26 | at LOS (WP: M.Buehrle; LP: A.Harang) | W - 6-2 | Wrap | Box |
| 8/288/288/288/288/29 | vs. WAS (WP: R.Nolasco; LP: S.Strasburg) | W - 9-0 | Wrap | Box |
| 8/298/298/298/298/30 | vs. WAS (WP: R.Detwiler; LP: J.Turner) | L - 4-8 | Wrap | Box |
| 8/318/318/318/319/01 | vs. NYM (WP: R.Dickey; LP: N.Eovaldi) | L - 0-3 | Wrap | Box |
| September |
| 9/019/019/019/019/02 | vs. NYM (WP: R.Ramirez; LP: S.Cishek) | L - 3-5 | Wrap | Box |
| 9/029/029/029/029/02 | vs. NYM (WP: C.Young; LP: M.Buehrle) | L - 1-5 | Wrap | Box |
| 9/039/039/039/039/03 | vs. MIL (WP: R.Nolasco; LP: M.Fiers) | W - 7-3 | Wrap | Box |
| 9/049/049/049/049/05 | vs. MIL (WP: K.Loe; LP: M.Dunn) | L - 4-8 | Wrap | Box |
| 9/059/059/059/059/06 | vs. MIL (WP: W.Peralta; LP: N.Eovaldi) | L - 5-8 | Wrap | Box |
| 9/069/069/069/069/06 | vs. MIL (WP: J.Johnson; LP: M.Estrada) | W - 6-2 | Wrap | Box |
| 9/079/079/079/079/08 | at WAS (WP: C.Gaudin; LP: T.Clippard) | W - 9-7 (10th) | Wrap | Box |
| 9/089/089/089/089/08 | at WAS (WP: D.Storen; LP: C.Gaudin) | L - 6-7 (10th) | Wrap | Box |
| 9/099/099/099/099/09 | at WAS (WP: R.Nolasco; LP: E.Jackson) | W - 8-0 | Wrap | Box |
| 9/109/109/109/109/11 | at PHI (WP: K.Kendrick; LP: W.LeBlanc) | L - 1-3 | Wrap | Box |
| 9/119/119/119/119/12 | at PHI (WP: R.Halladay; LP: N.Eovaldi) | L - 7-9 | Wrap | Box |
| 9/129/129/129/129/12 | at PHI (WP: C.Lee; LP: J.Johnson) | L - 1-3 | Wrap | Box |
| 9/149/149/149/149/15 | vs. CIN (WP: J.Turner; LP: B.Arroyo) | W - 4-0 | Wrap | Box |
| 9/159/159/159/159/16 | vs. CIN (WP: M.Buehrle; LP: J.Cueto) | W - 6-4 | Wrap | Box |
| 9/169/169/169/169/16 | vs. CIN (WP: L.Ondrusek; LP: C.Zambrano) | L - 4-5 (11th) | Wrap | Box |
| 9/179/179/179/179/18 | vs. ATL (WP: T.Hudson; LP: W.LeBlanc) | L - 5-7 | Wrap | Box |
| 9/189/189/189/189/19 | vs. ATL (WP: H.Bell; LP: C.Gearrin) | W - 4-3 (10th) | Wrap | Box |
| 9/199/199/199/199/20 | vs. ATL (WP: K.Medlen; LP: J.Johnson) | L - 0-3 | Wrap | Box |
| 9/219/219/219/219/22 | at NYM (WP: J.Niese; LP: J.Turner) | L - 3-7 | Wrap | Box |
| 9/229/229/229/229/22 | at NYM (WP: R.Dickey; LP: M.Buehrle) | L - 3-4 | Wrap | Box |
| 9/239/239/239/239/23 | at NYM (WP: B.Parnell; LP: R.Webb) | L - 2-3 | Wrap | Box |
| 9/259/259/259/259/26 | at ATL (WP: C.Kimbrel; LP: M.Dunn) | L - 3-4 | Wrap | Box |
| 9/269/269/269/269/27 | at ATL (WP: P.Maholm; LP: J.Johnson) | L - 0-3 | Wrap | Box |
| 9/279/279/279/279/28 | at ATL (WP: T.Hanson; LP: J.Turner) | L - 2-6 | Wrap | Box |
| 9/289/289/289/289/29 | vs. PHI (WP: S.Cishek; LP: J.Lindblom) | W - 2-1 | Wrap | Box |
| 9/299/299/299/299/30 | vs. PHI (WP: R.Halladay; LP: R.Nolasco) | L - 5-9 | Wrap | Box |
| 9/309/309/309/309/30 | vs. PHI (WP: C.Hamels; LP: N.Eovaldi) | L - 1-4 | Wrap | Box |
| October |
| 10/0110/0110/0110/0110/02 | vs. NYM (WP: H.Bell; LP: R.Ramirez) | W - 3-2 | Wrap | Box |
| 10/0210/0210/0210/0210/03 | vs. NYM (WP: C.Gaudin; LP: C.McHugh) | W - 4-3 (11th) | Wrap | Box |
| 10/0310/0310/0310/0310/03 | vs. NYM (WP: J.Hefner; LP: T.Koehler) | L - 2-4 | Wrap | Box |
