Wimbledon, England (Sports Network) - Three-time semifinalist Andy Murray and three-time runner-up Andy Roddick were a pair of second-round victors Thursday at The Championships, Wimbledon.

The fourth-seeded Murray snuck past massive-serving 6-foot-10 Croat Ivo Karlovic 7-5, 6-7 (5-7), 6-2, 7-6 (7-4) in just over three hours on Centre Court, while the 30th-seeded Roddick struck 13 aces and was broken only once in getting past speedy German Bjorn Phau 6-3, 7-6 (7-1), 6-3 in just over two hours on Court 2. Murray broke Karlovic, who smacked 17 aces, four times while being broken only once on Day 4.

Murray, who reached the semis here the previous three years, is trying to give Britain its first male Wimbledon champion since Fred Perry in 1936.

The former world No. 1 and former U.S. Open champion Roddick lost to the great Roger Federer in a trio of finals at the venerable All England Lawn tennis Club. The big-hitting American will meet seventh-seeded Spaniard David Ferrer on Saturday.

Ferrer, fresh off his grass-court title in the Netherlands last week, handled France's Kenny de Schepper 7-6 (7-1), 6-2, 6-4.

Meanwhile, Belgian Xavier Malisse doused 13th-seeded Frenchman Gilles Simon 6-4, 6-4, 7-6 (7-5) and 16th-seeded Croat Marin Cilic dismissed Poland's Lukasz Kubot 7-6 (7-4), 6-2, 6-1. Simon, a member of the ATP Player Council, drew some attention here on Wednesday when he said women should not earn the same prize money as the men at Grand Slam events.

In other action involving seeds, No. 17 Spaniard Fernando Verdasco held off Slovenian Grega Zemlja 7-6 (7-4), 7-6 (7-4), 3-6, 6-3, No. 19 Japanese Kei Nishikori beat Frenchman Florent Serra 6-3, 7-5, 6-2, and No. 28 Czech Radek Stepanek erased German Benjamin Becker 6-2, 7-6 (7-4), 6-3.

Additionally, American comeback kid Brian Baker whipped Finnish veteran Jarkko Nieminen 6-0, 6-2, 6-4, while Belgian David Goffin overcame American Jesse Levine 4-6, 6-4, 6-1, 6-3, and Colombian Alejandro Falla outlasted Frenchman Nicolas Mahut 6-4, 6-3, 4-6, 4-6, 7-5.

06/28 12:58:16 ET