| Starting Lineup: MLB-National at MLB-American |
| MLB-National | | MLB-American | | Pos. | Player | HR | RBI | AVG | | Pos. | Player | HR | RBI | AVG | | DH | Gonzalez, Carlos | 17 | 58 | .330 | | SS | Jeter, Derek | 7 | 25 | .308 | | CF | Cabrera, Melky | 8 | 44 | .353 | | 2B | Cano, Robinson | 20 | 51 | .313 | | LF | Braun, Ryan | 24 | 61 | .306 | | LF | Hamilton, Josh | 27 | 75 | .308 | | 1B | Votto, Joey | 14 | 48 | .348 | | RF | Bautista, Jose | 27 | 65 | .244 | | RF | Beltran, Carlos | 20 | 65 | .296 | | 1B | Fielder, Prince | 15 | 63 | .299 | | C | Posey, Buster | 10 | 43 | .289 | | 3B | Beltre, Adrian | 15 | 54 | .326 | | 3B | Sandoval, Pablo | 8 | 30 | .307 | | DH | Ortiz, David | 22 | 57 | .312 | | 2B | Uggla, Dan | 12 | 45 | .221 | | C | Napoli, Mike | 12 | 30 | .228 | | SS | Furcal, Rafael | 5 | 36 | .275 | | CF | Granderson, Curtis | 23 | 48 | .248 | | P | Cain, Matt (9-3, 2.62) | | P | Verlander, Justin (9-5, 2.58) |
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