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| 4th Quarter |
|
| Syracuse at 15:00 |
| 2nd and 4 at LOUISVILLE 30 | 4th quarter under way. |
| 2nd and 4 at LOUISVILLE 30 | Prince-Tyson Gulley rushed to the Louisville 27 for 3 yards. |
| 3rd and 1 at LOUISVILLE 27 | Prince-Tyson Gulley rushed to the Louisville 25 for 2 yards. |
| 1st and 10 at LOUISVILLE 25 | Prince-Tyson Gulley rushed for no gain. |
| 2nd and 10 at LOUISVILLE 25 | Alec Lemon on an end around for no gain. |
| 3rd and 10 at LOUISVILLE 25 | Ryan Nassib pass to Alec Lemon to the Louisville 14 for 11 yards. |
| 1st and 10 at LOUISVILLE 14 | Prince-Tyson Gulley rushed to the Louisville 10 for 4 yards. |
| 2nd and 6 at LOUISVILLE 10 | Adonis Ameen-Moore rushed to the Louisville 3 for 7 yards. |
| 1st and 3 at LOUISVILLE 3 | 3-yard run by Ryan Nassib to Lewellyn Coker. |
| | Ross Krautman extra point is good. |
| | Ryan Norton kicks 65 yards from the Syracuse 35 into the end zone for a touchback. |
| Louisville at 11:14 |
| 1st and 10 at LOUISVILLE 25 | Offensive penalty on Louisville, Unnecessary Roughness, 12 yards, enforced at the Louisville 25. |
| 1st and 22 at LOUISVILLE 13 | Teddy Bridgewater pass to Damian Copeland to the Louisville 20 for 7 yards. |
| 2nd and 15 at LOUISVILLE 20 | Teddy Bridgewater pass to Eli Rogers to the Louisville 25 for 5 yards. |
| 1st and 10 at LOUISVILLE 25 | Teddy Bridgewater pass to Andrell Smith to the Syracuse 47 for 28 yards. |
| 1st and 10 at SYRACUSE 47 | Teddy Bridgewater pass to Damian Copeland to the Syracuse 38 for 9 yards. |
| 2nd and 1 at SYRACUSE 38 | Teddy Bridgewater pass incomplete to Jeremy Wright. |
| 3rd and 1 at SYRACUSE 38 | Teddy Bridgewater rushed for 2 yards. |
| 1st and 10 at SYRACUSE 36 | Teddy Bridgewater pass to Scott Radcliff to the Syracuse 8 for 28 yards. |
| 1st and 8 at SYRACUSE 8 | Teddy Bridgewater pass incomplete. |
| 2nd and 8 at SYRACUSE 8 | 8-yard pass from Teddy Bridgewater to DeVante Parker. |
| | John Wallace extra point is good. |
| | John Wallace kicked off 63 yards from the Louisville 35 to the Syracuse 2. Jeremiah Kobena to the Syracuse 17 for 15 yards. |
| Syracuse at 8:35 |
| 1st and 10 at SYRACUSE 17 | Prince-Tyson Gulley rushed for 1 yard. |
| 2nd and 9 at SYRACUSE 18 | Prince-Tyson Gulley rushed for 2 yards. |
| 3rd and 7 at SYRACUSE 20 | Prince-Tyson Gulley rushed for 4 yards. |
| 4th and 3 at SYRACUSE 24 | Jonathan Fisher punted 40 yards from the Syracuse 24 to the Louisville 36. Kai Dominguez returned to the Louisville 37 for 1 yard. |
| Louisville at 6:24 |
| 1st and 10 at LOUISVILLE 37 | Offensive penalty on Louisville, Jamon Brown, False Start, 5 yards, enforced at the Louisville 37. |
| 1st and 15 at LOUISVILLE 32 | Teddy Bridgewater pass to Damian Copeland to the Louisville 39 for 7 yards. |
| 2nd and 8 at LOUISVILLE 39 | Defensive penalty on Syracuse, Robert Welsh, Roughing the Passer, 15 yards, enforced at the Louisville 39. |
| 1st and 10 at SYRACUSE 46 | Teddy Bridgewater pass to Jeremy Wright to the Syracuse 37 for 9 yards. |
| 2nd and 1 at SYRACUSE 37 | Teddy Bridgewater pass to Eli Rogers to the Syracuse 32 for 5 yards. |
| 1st and 10 at SYRACUSE 32 | Teddy Bridgewater pass to Jeremy Wright to the Syracuse 27 for 5 yards. |
| 2nd and 5 at SYRACUSE 27 | Teddy Bridgewater pass intercepted by Dyshawn Davis at the Syracuse 8 returned to the Syracuse 35 for 27 yards. |
| Syracuse at 3:52 |
| 1st and 10 at SYRACUSE 35 | Adonis Ameen-Moore rushed for 2 yards. |
| 2nd and 8 at SYRACUSE 37 | Adonis Ameen-Moore rushed for 7 yards. |
| 3rd and 1 at SYRACUSE 44 | Adonis Ameen-Moore rushed for 1 yard. |
| 1st and 10 at SYRACUSE 45 | Adonis Ameen-Moore rushed to the Louisville 49 for 6 yards. |
| 2nd and 4 at LOUISVILLE 49 | Adonis Ameen-Moore rushed for no gain. |
| 3rd and 4 at LOUISVILLE 49 | Adonis Ameen-Moore rushed to the Louisville 42 for 7 yards. |
| 1st and 10 at LOUISVILLE 42 | Team Team kneels to the Louisville 44 for -2 yards. |
