| April |
| 4/064/064/064/064/07 | vs. KAN (WP: J.Weaver; LP: A.Crow) | W - 5-0 | Wrap | Box |
| 4/074/074/074/074/07 | vs. KAN (WP: L.Hochevar; LP: D.Haren) | L - 3-6 | Wrap | Box |
| 4/084/084/084/084/08 | vs. KAN (WP: J.Sanchez; LP: E.Santana) | L - 3-7 | Wrap | Box |
| 4/094/094/094/094/09 | at MIN (WP: C.Wilson; LP: N.Blackburn) | W - 5-1 | Wrap | Box |
| 4/114/114/114/114/12 | at MIN (WP: J.Gray; LP: H.Takahashi) | L - 5-6 | Wrap | Box |
| 4/124/124/124/124/12 | at MIN (WP: J.Gray; LP: R.Thompson) | L - 9-10 | Wrap | Box |
| 4/134/134/134/134/13 | at NYY (WP: H.Kuroda; LP: E.Santana) | L - 0-5 | Wrap | Box |
| 4/144/144/144/144/14 | at NYY (WP: C.Wilson; LP: P.Hughes) | W - 7-1 | Wrap | Box |
| 4/154/154/154/154/16 | at NYY (WP: I.Nova; LP: J.Williams) | L - 5-11 | Wrap | Box |
| 4/164/164/164/164/17 | vs. OAK (WP: J.Weaver; LP: B.McCarthy) | W - 6-0 | Wrap | Box |
| 4/174/174/174/174/18 | vs. OAK (WP: B.Fuentes; LP: K.Jepsen) | L - 3-5 | Wrap | Box |
| 4/184/184/184/184/19 | vs. OAK (WP: B.Colon; LP: E.Santana) | L - 0-6 | Wrap | Box |
| 4/194/194/194/194/20 | vs. OAK (WP: T.Milone; LP: C.Wilson) | L - 2-4 | Wrap | Box |
| 4/204/204/204/204/21 | vs. BAL (WP: J.Williams; LP: B.Matusz) | W - 6-3 | Wrap | Box |
| 4/214/214/214/214/22 | vs. BAL (WP: J.Weaver; LP: J.Arrieta) | W - 6-3 | Wrap | Box |
| 4/224/224/224/224/22 | vs. BAL (WP: P.Strop; LP: L.Hawkins) | L - 2-3 (10th) | Wrap | Box |
| 4/244/244/244/244/25 | at TAM (WP: D.Price; LP: E.Santana) | L - 0-5 | Wrap | Box |
| 4/254/254/254/254/26 | at TAM (WP: J.Hellickson; LP: C.Wilson) | L - 2-3 | Wrap | Box |
| 4/264/264/264/264/26 | at TAM (WP: B.Gomes; LP: J.Walden) | L - 3-4 | Wrap | Box |
| 4/274/274/274/274/28 | at CLE (WP: V.Pestano; LP: D.Carpenter) | L - 2-3 | Wrap | Box |
| 4/284/284/284/284/28 | at CLE (WP: D.Haren; LP: J.Gomez) | W - 2-1 | Wrap | Box |
| 4/294/294/294/294/29 | at CLE (WP: D.Lowe; LP: E.Santana) | L - 0-4 | Wrap | Box |
| 4/304/304/304/305/01 | vs. MIN (WP: C.Wilson; LP: N.Blackburn) | W - 4-3 | Wrap | Box |
| May |
| 5/015/015/015/015/02 | vs. MIN (WP: J.Williams; LP: F.Liriano) | W - 4-0 | Wrap | Box |
| 5/025/025/025/025/03 | vs. MIN (WP: J.Weaver; LP: L.Hendriks) | W - 9-0 | Wrap | Box |
| 5/035/035/035/035/04 | vs. TOR (WP: B.Morrow; LP: D.Haren) | L - 0-5 | Wrap | Box |
| 5/045/045/045/045/05 | vs. TOR (WP: H.Alvarez; LP: E.Santana) | L - 0-4 | Wrap | Box |
| 5/055/055/055/055/06 | vs. TOR (WP: C.Wilson; LP: K.Drabek) | W - 6-2 | Wrap | Box |
| 5/065/065/065/065/06 | vs. TOR (WP: J.Williams; LP: D.Hutchison) | W - 4-3 | Wrap | Box |
| 5/075/075/075/075/08 | at MIN (WP: J.Weaver; LP: F.Liriano) | W - 8-3 | Wrap | Box |
| 5/085/085/085/085/09 | at MIN (WP: S.Diamond; LP: D.Haren) | L - 0-5 | Wrap | Box |
| 5/095/095/095/095/10 | at MIN (WP: E.Santana; LP: C.Pavano) | W - 6-2 | Wrap | Box |
| 5/115/115/115/115/12 | at TEX (WP: Y.Darvish; LP: C.Wilson) | L - 3-10 | Wrap | Box |
| 5/125/125/125/125/12 | at TEX (WP: D.Carpenter; LP: M.Harrison) | W - 4-2 | Wrap | Box |
| 5/135/135/135/135/14 | at TEX (WP: N.Feliz; LP: J.Weaver) | L - 6-13 | Wrap | Box |
| 5/145/145/145/145/15 | vs. OAK (WP: T.Ross; LP: D.Haren) | L - 0-5 | Wrap | Box |
| 5/155/155/155/155/16 | vs. OAK (WP: E.Santana; LP: B.Colon) | W - 4-0 | Wrap | Box |
| 5/165/165/165/165/17 | vs. CWS (WP: J.Williams; LP: G.Floyd) | W - 7-2 | Wrap | Box |
| 5/175/175/175/175/17 | vs. CWS (WP: C.Sale; LP: C.Wilson) | L - 1-6 | Wrap | Box |
| 5/185/185/185/185/19 | at SDP (WP: J.Weaver; LP: J.Suppan) | W - 7-2 | Wrap | Box |
| 5/195/195/195/195/20 | at SDP (WP: L.Gregerson; LP: D.Haren) | L - 2-3 | Wrap | Box |
| 5/205/205/205/205/20 | at SDP (WP: M.Mikolas; LP: D.Pauley) | L - 2-3 (13th) | Wrap | Box |
| 5/215/215/215/215/22 | at OAK (WP: T.Milone; LP: J.Williams) | L - 1-2 | Wrap | Box |
| 5/225/225/225/225/23 | at OAK (WP: C.Wilson; LP: G.Godfrey) | W - 5-0 | Wrap | Box |
| 5/235/235/235/235/23 | at OAK (WP: J.Walden; LP: J.Norberto) | W - 3-1 (11th) | Wrap | Box |
| 5/245/245/245/245/25 | at SEA (WP: D.Haren; LP: J.Vargas) | W - 3-0 | Wrap | Box |
| 5/255/255/255/255/26 | at SEA (WP: J.Isringhausen; LP: B.League) | W - 6-4 | Wrap | Box |
| 5/265/265/265/265/27 | at SEA (WP: J.Williams; LP: F.Hernandez) | W - 5-3 | Wrap | Box |
| 5/275/275/275/275/27 | at SEA (WP: C.Wilson; LP: H.Noesi) | W - 4-2 | Wrap | Box |
| 5/285/285/285/285/29 | vs. NYY (WP: J.Walden; LP: C.Wade) | W - 9-8 | Wrap | Box |
| 5/295/295/295/295/30 | vs. NYY (WP: D.Haren; LP: A.Pettitte) | W - 5-1 | Wrap | Box |
| 5/305/305/305/305/31 | vs. NYY (WP: I.Nova; LP: H.Takahashi) | L - 5-6 | Wrap | Box |
| June |
| 6/016/016/016/016/02 | vs. TEX (WP: J.Williams; LP: C.Lewis) | W - 4-2 | Wrap | Box |
| 6/026/026/026/026/03 | vs. TEX (WP: B.Cassevah; LP: Y.Darvish) | W - 3-2 | Wrap | Box |
| 6/036/036/036/036/03 | vs. TEX (WP: M.Harrison; LP: D.Haren) | L - 3-7 | Wrap | Box |
| 6/046/046/046/046/05 | vs. SEA (WP: J.Vargas; LP: E.Santana) | L - 6-8 | Wrap | Box |
| 6/056/056/056/056/06 | vs. SEA (WP: G.Richards; LP: B.Beavan) | W - 6-1 | Wrap | Box |
| 6/066/066/066/066/07 | vs. SEA (WP: S.Kelley; LP: J.Williams) | L - 6-8 | Wrap | Box |
| 6/086/086/086/086/09 | at COL (WP: C.Wilson; LP: A.White) | W - 7-2 | Wrap | Box |
| 6/096/096/096/096/09 | at COL (WP: D.Haren; LP: J.Francis) | W - 11-5 | Wrap | Box |
| 6/106/106/106/106/10 | at COL (WP: E.Santana; LP: C.Friedrich) | W - 10-8 | Wrap | Box |
| 6/116/116/116/116/12 | at LOS (WP: J.Isringhausen; LP: K.Jansen) | W - 3-2 | Wrap | Box |
| 6/126/126/126/126/13 | at LOS (WP: J.Wright; LP: J.Williams) | L - 2-5 | Wrap | Box |
| 6/136/136/136/136/14 | at LOS (WP: L.Hawkins; LP: K.Jansen) | W - 2-1 | Wrap | Box |
| 6/156/156/156/156/16 | vs. ARI (WP: T.Cahill; LP: D.Haren) | L - 0-5 | Wrap | Box |
| 6/166/166/166/166/17 | vs. ARI (WP: E.Santana; LP: J.Saunders) | W - 2-0 | Wrap | Box |
| 6/176/176/176/176/17 | vs. ARI (WP: G.Richards; LP: I.Kennedy) | W - 2-0 | Wrap | Box |
| 6/186/186/186/186/19 | vs. SFG (WP: M.Cain; LP: J.Williams) | L - 3-5 | Wrap | Box |
| 6/196/196/196/196/20 | vs. SFG (WP: C.Wilson; LP: B.Zito) | W - 12-5 | Wrap | Box |
| 6/206/206/206/206/21 | vs. SFG (WP: J.Weaver; LP: R.Vogelsong) | W - 6-0 | Wrap | Box |
| 6/226/226/226/226/23 | vs. LOS (WP: D.Haren; LP: C.Billingsley) | W - 8-5 | Wrap | Box |
| 6/236/236/236/236/24 | vs. LOS (WP: C.Capuano; LP: E.Santana) | L - 1-3 | Wrap | Box |
| 6/246/246/246/246/24 | vs. LOS (WP: S.Downs; LP: J.Lindblom) | W - 5-3 | Wrap | Box |
| 6/266/266/266/266/27 | at BAL (WP: C.Wilson; LP: B.Matusz) | W - 7-3 | Wrap | Box |
| 6/276/276/276/276/28 | at BAL (WP: J.Weaver; LP: J.Hammel) | W - 13-1 | Wrap | Box |
| 6/286/286/286/286/29 | at TOR (WP: D.Haren; LP: B.Cecil) | W - 9-7 | Wrap | Box |
| 6/296/296/296/296/30 | at TOR (WP: F.Cordero; LP: J.Walden) | L - 5-7 | Wrap | Box |
| 6/306/306/306/306/30 | at TOR (WP: H.Alvarez; LP: G.Richards) | L - 2-11 | Wrap | Box |
| July |
| 7/017/017/017/017/01 | at TOR (WP: J.Isringhausen; LP: F.Cordero) | W - 10-6 | Wrap | Box |
| 7/027/027/027/027/03 | at CLE (WP: J.Weaver; LP: U.Jimenez) | W - 3-0 | Wrap | Box |
| 7/037/037/037/037/04 | at CLE (WP: Z.McAllister; LP: D.Haren) | L - 5-9 | Wrap | Box |
| 7/047/047/047/047/04 | at CLE (WP: D.Lowe; LP: E.Santana) | L - 3-12 | Wrap | Box |
| 7/057/057/057/057/06 | vs. BAL (WP: L.Hawkins; LP: L.Ayala) | W - 9-7 | Wrap | Box |
| 7/067/067/067/067/07 | vs. BAL (WP: M.Gonzalez; LP: C.Wilson) | L - 2-3 | Wrap | Box |
| 7/077/077/077/077/08 | vs. BAL (WP: J.Weaver; LP: J.Hammel) | W - 3-0 | Wrap | Box |
| 7/087/087/087/087/08 | vs. BAL (WP: B.Mills; LP: W.Chen) | W - 6-0 | Wrap | Box |
| 7/137/137/137/137/14 | at NYY (WP: C.Qualls; LP: S.Downs) | L - 5-6 | Wrap | Box |
| 7/147/147/147/147/14 | at NYY (WP: F.Garcia; LP: J.Williams) | L - 3-5 | Wrap | Box |
| 7/157/157/157/157/15 | at NYY (WP: J.Weaver; LP: I.Nova) | W - 10-8 | Wrap | Box |
| 7/167/167/167/167/17 | at DET (WP: O.Dotel; LP: L.Hawkins) | L - 6-8 | Wrap | Box |
| 7/177/177/177/177/18 | at DET (WP: G.Richards; LP: J.Turner) | W - 13-0 | Wrap | Box |
| 7/187/187/187/187/19 | at DET (WP: D.Fister; LP: C.Wilson) | L - 2-7 | Wrap | Box |
| 7/197/197/197/197/19 | at DET (WP: M.Scherzer; LP: J.Williams) | L - 1-5 | Wrap | Box |
| 7/207/207/207/207/21 | vs. TEX (WP: J.Weaver; LP: D.Holland) | W - 6-1 | Wrap | Box |
| 7/217/217/217/217/21 | vs. TEX (WP: Y.Darvish; LP: E.Santana) | L - 2-9 | Wrap | Box |
| 7/227/227/227/227/23 | vs. TEX (WP: D.Haren; LP: M.Harrison) | W - 7-4 | Wrap | Box |
| 7/237/237/237/237/24 | vs. KAN (WP: K.Jepsen; LP: G.Holland) | W - 6-3 | Wrap | Box |
| 7/247/247/247/247/25 | vs. KAN (WP: W.Smith; LP: G.Richards) | L - 1-4 | Wrap | Box |
| 7/257/257/257/257/25 | vs. KAN (WP: J.Weaver; LP: L.Hochevar) | W - 11-6 | Wrap | Box |
| 7/277/277/277/277/28 | vs. TAM (WP: D.Haren; LP: A.Cobb) | W - 3-1 | Wrap | Box |
| 7/287/287/287/287/29 | vs. TAM (WP: M.Moore; LP: C.Wilson) | L - 0-3 | Wrap | Box |
| 7/297/297/297/297/29 | vs. TAM (WP: J.Hellickson; LP: Z.Greinke) | L - 0-2 | Wrap | Box |
| 7/307/307/307/307/31 | at TEX (WP: E.Santana; LP: R.Oswalt) | W - 15-8 | Wrap | Box |
| 7/317/317/317/318/01 | at TEX (WP: J.Weaver; LP: D.Holland) | W - 6-2 | Wrap | Box |
| August |
| 8/018/018/018/018/02 | at TEX (WP: J.Nathan; LP: J.Isringhausen) | L - 10-11 (10th) | Wrap | Box |
| 8/028/028/028/028/03 | at TEX (WP: R.Oswalt; LP: D.Carpenter) | L - 9-15 | Wrap | Box |
| 8/038/038/038/038/04 | at CWS (WP: M.Thornton; LP: H.Takahashi) | L - 6-8 (10th) | Wrap | Box |
| 8/048/048/048/048/05 | at CWS (WP: K.Jepsen; LP: M.Thornton) | W - 6-5 (10th) | Wrap | Box |
| 8/058/058/058/058/05 | at CWS (WP: N.Jones; LP: J.Isringhausen) | L - 2-4 | Wrap | Box |
| 8/068/068/068/068/07 | at OAK (WP: J.Weaver; LP: J.Parker) | W - 4-0 | Wrap | Box |
| 8/078/078/078/078/08 | at OAK (WP: B.Colon; LP: C.Wilson) | L - 4-10 | Wrap | Box |
| 8/088/088/088/088/08 | at OAK (WP: P.Neshek; LP: L.Hawkins) | L - 8-9 | Wrap | Box |
| 8/108/108/108/108/11 | vs. SEA (WP: E.Frieri; LP: J.Kinney) | W - 6-5 | Wrap | Box |
| 8/118/118/118/118/12 | vs. SEA (WP: H.Iwakuma; LP: D.Haren) | L - 4-7 | Wrap | Box |
| 8/128/128/128/128/12 | vs. SEA (WP: J.Vargas; LP: J.Weaver) | L - 1-4 | Wrap | Box |
| 8/138/138/138/138/14 | vs. CLE (WP: J.Masterson; LP: C.Wilson) | L - 2-6 | Wrap | Box |
| 8/148/148/148/148/15 | vs. CLE (WP: Z.Greinke; LP: U.Jimenez) | W - 9-6 | Wrap | Box |
| 8/158/158/158/158/16 | vs. CLE (WP: E.Santana; LP: R.Hernandez) | W - 8-4 | Wrap | Box |
| 8/168/168/168/168/17 | vs. TAM (WP: D.Price; LP: D.Haren) | L - 0-7 | Wrap | Box |
| 8/178/178/178/178/18 | vs. TAM (WP: J.Shields; LP: J.Weaver) | L - 3-12 | Wrap | Box |
| 8/188/188/188/188/19 | vs. TAM (WP: J.McGee; LP: K.Jepsen) | L - 8-10 | Wrap | Box |
| 8/198/198/198/198/19 | vs. TAM (WP: M.Moore; LP: Z.Greinke) | L - 3-8 | Wrap | Box |
| 8/218/218/218/218/22 | at BOS (WP: E.Santana; LP: A.Cook) | W - 5-3 | Wrap | Box |
| 8/228/228/228/228/23 | at BOS (WP: J.Weaver; LP: C.Buchholz) | W - 7-3 | Wrap | Box |
| 8/238/238/238/238/24 | at BOS (WP: E.Frieri; LP: A.Aceves) | W - 14-13 (10th) | Wrap | Box |
| 8/248/248/248/248/25 | at DET (WP: Z.Greinke; LP: R.Porcello) | W - 2-1 | Wrap | Box |
| 8/258/258/258/258/26 | at DET (WP: O.Dotel; LP: G.Richards) | L - 3-5 | Wrap | Box |
| 8/268/268/268/268/26 | at DET (WP: M.Scherzer; LP: E.Santana) | L - 2-5 | Wrap | Box |
| 8/288/288/288/288/29 | vs. BOS (WP: K.Jepsen; LP: A.Aceves) | W - 6-5 | Wrap | Box |
| 8/298/298/298/298/30 | vs. BOS (WP: C.Wilson; LP: Z.Stewart) | W - 10-3 | Wrap | Box |
| 8/308/308/308/308/31 | vs. BOS (WP: Z.Greinke; LP: J.Lester) | W - 5-2 | Wrap | Box |
| 8/318/318/318/319/01 | at SEA (WP: D.Haren; LP: K.Millwood) | W - 9-1 | Wrap | Box |
| September |
| 9/019/019/019/019/01 | at SEA (WP: E.Santana; LP: F.Hernandez) | W - 5-2 | Wrap | Box |
| 9/029/029/029/029/02 | at SEA (WP: H.Iwakuma; LP: J.Weaver) | L - 1-2 | Wrap | Box |
| 9/039/039/039/039/03 | at OAK (WP: C.Wilson; LP: T.Milone) | W - 8-3 | Wrap | Box |
| 9/049/049/049/049/05 | at OAK (WP: Z.Greinke; LP: J.Parker) | W - 6-1 | Wrap | Box |
| 9/059/059/059/059/05 | at OAK (WP: D.Haren; LP: B.McCarthy) | W - 7-1 | Wrap | Box |
| 9/079/079/079/079/08 | vs. DET (WP: E.Frieri; LP: O.Dotel) | W - 3-2 | Wrap | Box |
| 9/089/089/089/089/09 | vs. DET (WP: C.Wilson; LP: J.Verlander) | W - 6-1 | Wrap | Box |
| 9/099/099/099/099/09 | vs. DET (WP: Z.Greinke; LP: A.Sanchez) | W - 3-2 | Wrap | Box |
| 9/109/109/109/109/11 | vs. OAK (WP: J.Parker; LP: D.Haren) | L - 1-3 | Wrap | Box |
| 9/119/119/119/119/12 | vs. OAK (WP: D.Straily; LP: J.Williams) | L - 5-6 | Wrap | Box |
| 9/129/129/129/129/13 | vs. OAK (WP: A.Griffin; LP: E.Santana) | L - 1-4 | Wrap | Box |
| 9/139/139/139/139/13 | vs. OAK (WP: J.Weaver; LP: B.Anderson) | W - 6-0 | Wrap | Box |
| 9/149/149/149/149/15 | at KAN (WP: J.Walden; LP: T.Collins) | W - 9-7 | Wrap | Box |
| 9/159/159/159/159/16 | at KAN (WP: K.Herrera; LP: E.Frieri) | L - 2-3 | Wrap | Box |
| 9/169/169/169/169/16 | at KAN (WP: D.Haren; LP: W.Smith) | W - 4-3 | Wrap | Box |
| 9/189/189/189/189/19 | vs. TEX (WP: J.Weaver; LP: R.Dempster) | W - 11-3 | Wrap | Box |
| 9/199/199/199/199/20 | vs. TEX (WP: D.Holland; LP: C.Wilson) | L - 2-6 | Wrap | Box |
| 9/209/209/209/209/21 | vs. TEX (WP: Y.Darvish; LP: E.Frieri) | L - 1-3 | Wrap | Box |
| 9/219/219/219/219/22 | vs. CWS (WP: E.Santana; LP: J.Peavy) | W - 6-2 | Wrap | Box |
| 9/229/229/229/229/23 | vs. CWS (WP: D.Haren; LP: J.Quintana) | W - 4-2 | Wrap | Box |
| 9/239/239/239/239/23 | vs. CWS (WP: J.Weaver; LP: G.Floyd) | W - 4-1 | Wrap | Box |
| 9/259/259/259/259/26 | vs. SEA (WP: Z.Greinke; LP: E.Ramirez) | W - 5-4 | Wrap | Box |
| 9/269/269/269/269/27 | vs. SEA (WP: E.Frieri; LP: S.Pryor) | W - 4-3 | Wrap | Box |
| 9/279/279/279/279/27 | vs. SEA (WP: H.Iwakuma; LP: D.Haren) | L - 4-9 | Wrap | Box |
| 9/289/289/289/289/29 | at TEX (WP: J.Weaver; LP: R.Dempster) | W - 7-4 | Wrap | Box |
| 9/299/299/299/299/29 | at TEX | Postponed | Wrap |
| 9/309/309/309/309/30 | at TEX (WP: G.Richards; LP: J.Nathan) | W - 5-4 | Wrap | Box |
| 9/309/309/309/3010/01 | at TEX (WP: D.Holland; LP: E.Santana) | L - 7-8 | Wrap | Box |
| October |
| 10/0110/0110/0110/0110/02 | at SEA (WP: C.Wilson; LP: F.Hernandez) | W - 8-4 | Wrap | Box |
| 10/0210/0210/0210/0210/03 | at SEA (WP: H.Iwakuma; LP: D.Haren) | L - 1-6 | Wrap | Box |
| 10/0310/0310/0310/0310/03 | at SEA (WP: B.Beavan; LP: J.Weaver) | L - 0-12 | Wrap | Box |
