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Week 4 will present a pivotal matchup for most fantasy teams.
The 2-1 teams want to continue their rise, the 1-2 teams don't want to fall to 1-3 and the 0-3 teams are facing a must-win. And the 3-0 teams? Well, let's hope they all lose.
To help you with your teams, here are some predictions for this week's games.
Baltimore at Buffalo
Ray Rice and Bernard Pierce will both be top-25 running backs in Week 4.
C.J. Spiller will find the end zone for the first time and produce 100 yards from scrimmage, while Fred Jackson will run for under 3.0 yards per carry.
Cincinnati at Cleveland
Giovani Bernard will continue run circles around BenJarvus Green-Ellis and is a high-end RB2 this week.
Josh Gordon will have another 100-yard game or a touchdown.
Chicago at Detroit
Martellus Bennett, Brandon Marshall and Matt Forte will all have more than 10 fantasy points in standard leagues.
Ryan Broyles will catch seven passes for 75 yards and a touchdown.
New York Giants at Kansas City
Hakeem Nicks will score his first touchdown of the season after being shut out in Week 3.
Dwayne Bowe will have less than 65 receiving yards again.
Arizona at Tampa Bay
Larry Fitzgerald will be held without a touchdown for the third straight week.
Doug Martin will have 150 yards from scrimmage and a touchdown.
Indianapolis at Jacksonville
Trent Richardson will run for 125 yards and a touchdown.
Maurice Jones-Drew will reach 100 yards from scrimmage and find the end zone.
Seattle at Houston
Marshawn Lynch will bounce back with 80 rushing yards and a touchdown.
Arian Foster will finish outside the top-20 running backs in Week 4.
Pittsburgh at Minnesota
Antonio Brown will have less than 100 yards and won't score.
Matt Cassel won't be an upgrade on Christian Ponder and no Minnesota receiver will do anything fantasy-worthy.
New York Jets at Tennessee
Santonio Holmes, Stephen Hill and Bilal Powell all will be held under 100 yards, but Holmes and Powell will score touchdowns.
Chris Johnson will fail to reach 100 rushing yards but will have more than 80 again.
Washington at Oakland
Robert Griffin III will throw for two touchdowns and run for another.
Darren McFadden will be a top-10 fantasy running back this week.
Philadelphia at Denver
Michael Vick will rejoin the top-five fantasy quarterbacks.
Demaryius Thomas will have his best game since Week 1.
Dallas at San Diego
DeMarco Murray won't rush for 100 yards or score a touchdown.
No San Diego wide receiver will produce 100 yards or a touchdown, but Antonio Gates will.
New England at Atlanta
Rob Gronkowski will score two touchdowns if he plays.
Jason Snelling will have 100 yards from scrimmage again, and Jacquizz Rodgers will have under 60 rushing yards.
Miami at New Orleans
Ryan Tannehill will throw for less than 200 yards with just one touchdown and two turnovers.
Marques Colston will score a touchdown for the first time since Week 1.
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