| Week 1 | 9/099/099/099/099/10 | at San Diego Tickets | 10:20 PM ET9:20 PM CT8:20 PM MT7:20 PM PT3:20 AM GMT | ESPN |
| Week 2 | 9/159/159/159/159/15 | vs Tennessee Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 3 | 9/229/229/229/229/22 | at Baltimore Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 4 | 9/299/299/299/299/29 | vs Seattle Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | FOX |
| Week 5 | 10/0610/0610/0610/0610/07 | at San Francisco Tickets | 8:30 PM ET7:30 PM CT6:30 PM MT5:30 PM PT1:30 AM GMT | NBC |
| Week 6 | 10/1310/1310/1310/1310/13 | vs St. Louis Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | FOX |
| Week 7 | 10/2010/2010/2010/2010/20 | at Kansas City Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 8 | 10/2710/2710/2710/2710/28 | Bye | | |
| Week 9 | 11/0311/0311/0311/0311/04 | vs Indianapolis Tickets | 8:30 PM ET7:30 PM CT6:30 PM MT5:30 PM PT1:30 AM GMT | NBC |
| Week 10 | 11/1011/1011/1011/1011/10 | at Arizona Tickets | 4:25 PM ET3:25 PM CT2:25 PM MT1:25 PM PT9:25 PM GMT | CBS |
| Week 11 | 11/1711/1711/1711/1711/17 | vs Oakland Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 12 | 11/2411/2411/2411/2411/24 | vs Jacksonville Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 13 | 12/0112/0112/0112/0112/01 | vs New England Tickets | 4:25 PM ET3:25 PM CT2:25 PM MT1:25 PM PT9:25 PM GMT | CBS |
| Week 14 | 12/0512/0512/0512/0512/06 | at Jacksonville Tickets | 8:25 PM ET7:25 PM CT6:25 PM MT5:25 PM PT1:25 AM GMT | NFL Network |
| Week 15 | 12/1512/1512/1512/1512/15 | at Indianapolis Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 16 | 12/2212/2212/2212/2212/22 | vs Denver Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
| Week 17 | 12/2912/2912/2912/2912/29 | at Tennessee Tickets | 1:00 PM ET12:00 PM CT11:00 AM MT10:00 AM PT6:00 PM GMT | CBS |
