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| Scoring Summary |
| 1st Quarter |
| Louisville Touchdown - 29-yard pass from Teddy Bridgewater to DeVante Parker. (Team Team pass incomplete, two-point conversion failed). |
| Southern Miss Touchdown - 23-yard interception return by Reggie Hunt. (Corey Acosta extra point is good). |
| Southern Miss Field Goal - 21-yarder by Corey Acosta. |
| 2nd Quarter |
| Southern Miss Touchdown - 1-yard run by Jalen Richard. (Corey Acosta extra point is good). |
| Louisville Touchdown - 1-yard run by Senorice Perry. (Teddy Bridgewater pass incomplete to Eli Rogers, two-point conversion failed). |
| 3rd Quarter |
| Louisville Field Goal - 38-yarder by John Wallace. |
| 4th Quarter |
| Louisville Touchdown - 14-yard run by Senorice Perry. (John Wallace extra point blocked by Team). |
