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| 4th Quarter |
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| Tennessee at 15:00 |
| 1st and 10 at TEN 23 | 4th quarter under way. |
| 1st and 10 at TEN 23 | Chris Johnson rushed to the Tennessee 24 for 1 yard. |
| 2nd and 9 at TEN 24 | Matt Hasselbeck pass to Chris Johnson to the Tennessee 27 for 3 yards. |
| 3rd and 6 at TEN 27 | Matt Hasselbeck pass to Damian Williams to the Tennessee 35 for 8 yards. |
| 1st and 10 at TEN 35 | Chris Johnson rushed to the Tennessee 40 for 5 yards. |
| 2nd and 5 at TEN 40 | Chris Johnson rushed to the Tennessee 43 for 3 yards. |
| 3rd and 2 at TEN 43 | Matt Hasselbeck pass to Nate Washington to the Tennessee 47 for 4 yards. |
| 1st and 10 at TEN 47 | Jamie Harper rushed to the Tennessee 46 for -1 yards. |
| 2nd and 11 at TEN 46 | Matt Hasselbeck pass incomplete to Taylor Thompson. |
| 3rd and 11 at TEN 46 | Offensive penalty on Tennessee, Delay of Game, 5 yards, enforced at the Tennessee 46. |
| 3rd and 16 at TEN 41 | Matt Hasselbeck pass to Darius Reynaud to the 50 for 9 yards. |
| 4th and 7 at the 50 | Brett Kern punted 35 yards from the Buffalo 50 to the Buffalo 15 for a fair catch by Leodis McKelvin. |
| Buffalo at 9:22 |
| 1st and 10 at BUF 15 | C.J. Spiller rushed to the Buffalo 22 for 7 yards. |
| 2nd and 3 at BUF 22 | Ryan Fitzpatrick pass to Stevie Johnson to the Buffalo 28 for 6 yards. |
| 1st and 10 at BUF 28 | C.J. Spiller rushed to the Buffalo 29 for 1 yard. |
| 2nd and 9 at BUF 29 | Offensive penalty on Buffalo, Holding/Illegal Use of Hands, 10 yards, enforced at the Buffalo 29. |
| 2nd and 19 at BUF 19 | Ryan Fitzpatrick pass to C.J. Spiller to the Buffalo 14 for -5 yards. |
| 3rd and 24 at BUF 14 | Ryan Fitzpatrick rushed to the Buffalo 24 for 10 yards. |
| 4th and 14 at BUF 24 | Shawn Powell punted out of bounds at the Buffalo 46. |
| Tennessee at 5:29 |
| 1st and 10 at BUF 45 | Defensive penalty on Buffalo, Aaron Williams, Holding/Illegal Use of Hands, 5 yards, enforced at the Buffalo 45. |
| 1st and 10 at BUF 41 | Matt Hasselbeck pass to Nate Washington to the Buffalo 38 for 3 yards. |
| 2nd and 7 at BUF 38 | Matt Hasselbeck pass incomplete to Chris Johnson. |
| 3rd and 7 at BUF 38 | Matt Hasselbeck pass to Nate Washington to the Buffalo 36 for 2 yards. |
| 4th and 5 at BUF 36 | Matt Hasselbeck pass incomplete to Jared Cook. |
| Buffalo at 3:47 |
| 1st and 10 at BUF 36 | Fred Jackson rushed to the Buffalo 40 for 4 yards. |
| 2nd and 6 at BUF 40 | Ryan Fitzpatrick pass to C.J. Spiller to the Buffalo 39 for -1 yards. |
| 3rd and 7 at BUF 39 | Ryan Fitzpatrick pass intercepted by Jason McCourty at the Tennessee 48 returned for no gain. |
| Tennessee at 2:48 |
| 1st and 10 at TEN 48 | Matt Hasselbeck sacked by Kyle Williams for -8 yards. |
| 2nd and 18 at TEN 40 | Matt Hasselbeck pass to Nate Washington to the Buffalo 41 for 19 yards. Nate Washington fumble recovered by Tennessee at the Buffalo 43 returned for no gain. |
| 3rd and 1 at BUF 43 | Chris Johnson rushed to the Buffalo 16 for 27 yards. |
| 1st and 10 at BUF 16 | Jamie Harper rushed to the Buffalo 17 for -1 yards. |
| 2nd and 11 at BUF 17 | Matt Hasselbeck pass incomplete to Nate Washington. |
| 3rd and 11 at BUF 17 | Matt Hasselbeck pass to Nate Washington to the Buffalo 15 for 2 yards. |
| 4th and 9 at BUF 15 | 15-yard pass from Matt Hasselbeck to Nate Washington. |
| | Rob Bironas extra point is good. |
| | Rob Bironas kicks 65 yards from the Tennessee 35 into the end zone for a touchback. |
| Buffalo at 0:52 |
| 1st and 10 at BUF 20 | Ryan Fitzpatrick pass to Fred Jackson to the Buffalo 26 for 6 yards. |
| 2nd and 4 at BUF 26 | Ryan Fitzpatrick pass to Scott Chandler to the Buffalo 28 for 2 yards. |
| 3rd and 2 at BUF 28 | Ryan Fitzpatrick pass incomplete to Scott Chandler. |
| 4th and 2 at BUF 28 | Ryan Fitzpatrick pass incomplete to Stevie Johnson. |
| Tennessee at 0:23 |
| 1st and 10 at BUF 28 | Matt Hasselbeck kneels to the Buffalo 30 for -2 yards. |