| San Diego Padres (16-27) at St. Louis Cardinals (23-19) |
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| Game One |
St. Louis 4, San Diego 3 |
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| Game Two |
Tuesday, May 22nd, 8:15 p.m. |
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| Game Three |
Wednesday, May 23rd, 8:15 p.m. |
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| Records |
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| 2012 Head-to-Head Record |
St. Louis 1-0 (0-0 at SD; 1-0 at StL) |
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| 2011 Head-to-Head Record |
Tied 3-3 (StL 2-1 at SD; 1-2 at Home) |
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| 2010 Head-to-Head Record |
St. Louis 4-3 (1-2 at SD; 3-1 at StL) |
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| 2009 Head-to-Head Record |
St. Louis 6-1 (3-1 at SD; 3-0 at StL) |
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| Home Record |
San Diego 12-16; St. Louis 10-8 |
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| Away Record |
San Diego 4-11; St. Louis 13-11 |
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| Current Streak |
San Diego (L1); St. Louis (W1) |
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| Record vs. Central Division |
San Diego 2-2 |
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| Record vs. Western Division |
St. Louis 5-4 |
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| 2012 Meetings |
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| 5/21 - St. Louis, 4-3 (at StL - WP: Motte; LP: Cashner) |
| 2011 Meetings |
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| 3/31 - San Diego, 5-3 (11) (at StL - WP: Neshek; LP: Augenstein) |
| 4/02 - San Diego, 11-3 (at StL - WP: Richard; LP: Westbrook) |
| 4/03 - St. Louis, 2-0 (at StL - WP: J.Garcia; LP: Moseley) |
| 5/23 - St. Louis, 3-1 (at SD - WP: Lohse; LP: H.Bell) |
| 5/24 - St. Louis, 3-2 (11) (at SD - WP: Batista; LP: Frieri) |
| 5/25 - San Diego, 3-1 (at SD - WP: Latos; LP: C.Carpenter) |
| 2010 Meetings |
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| 5/25 - San Diego, 1-0 (at SD - WP: Garland; LP: Wainwright) |
| 5/26 - San Diego, 2-1 (13) (at SD - WP: Mujica; LP: Boggs) |
| 5/27 - St. Louis, 8-3 (at SD - WP: Walters; LP: LeBlanc) |
| 9/16 - St. Louis, 4-0 (at StL - WP: Westbrook; LP: Stauffer) |
| 9/17 - St. Louis, 14-4 (at StL - WP: Lohse; LP: Latos) |
| 9/18 - San Diego, 8-4 (at StL - WP: Adams; LP: McClellan) |
| 9/19 - St. Louis, 4-1 (at StL - WP: Wainwright; LP: Garland) |
| 2009 Meetings |
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| 8/14 - St. Louis, 9-2 (at StL - WP: Wainwright; LP: Latos) |
| 8/15 - St. Louis, 7-4 (at StL - WP: Pineiro; LP: Stauffer) |
| 8/16 - St. Louis, 7-5 (at StL - WP: T.Miller; LP: H.Bell) |
| 8/20 - St. Louis, 5-1 (at SD - WP: Pineiro; LP: Stauffer) |
| 8/21 - San Diego, 4-0 (at SD - WP: Richard; LP: Lohse) |
| 8/22 - St. Louis, 7-0 (at SD - WP: C.Carpenter; LP: Correia) |
| 8/23 - St. Louis, 5-2 (at SD - WP: Smoltz; LP: Carrillo) |
| San Diego last five games |
St. Louis last five games |
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| 5/17 - L vs. Los Angeles, 1-8 |
5/17 - L at San Francisco, 5-7 |
| 5/18 - L vs. LA Angels, 2-7 |
5/18 - L at Los Angeles, 5-6 |
| 5/19 - W vs. LA Angels, 3-2 |
5/19 - L at Los Angeles, 0-6 |
| 5/20 - W vs. LA Angels, 3-2 (13) |
5/20 - L at Los Angeles, 5-6 |
| 5/21 - L at St. Louis, 3-4 |
5/21 - W vs. San Diego, 4-3 |
